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Among the hcl most common adverse reactions associated with fluoxetine discontinuation (incidence at least twice that for placebo and at least 1 for prozac in clinical trials collecting only a primary reaction associated with discontinuation) in US placebo-controlled fluoxetine clinical. Prozac should be introduced with care in patients with a history of hcl seizures. Alcohol can also keep Prozac from working as well as it should. Clinical studies of pimozide with other antidepressants demonstrate an increase in drug interaction or fluoxetine QT prolongation. In these 3 studies, prozac 60 mg, but not 20 mg, was statistically significantly superior to placebo in reducing the number of binge-eating and vomiting episodes per week. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. The following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness hypomania, and mania, have been fluoxetine reported in adult and pediatric patients being treated with antidepressants for Major Depressive Disorder as well as for other indications, both psychiatric and nonpsychiatric. Fluoxetine side effects Get emergency medical help if you have signs of an allergic reaction to fluoxetine: fluoxetine skin rash or hives; difficulty breathing; swelling of your hcl face, lips, tongue, or throat. 3 Denominator used was for males only (N690 prozac Major Depressive Disorder; N410 placebo Major Depressive Disorder; N116 prozac OCD; N43 placebo OCD; N14 prozac bulimia; N1 placebo bulimia; N162 prozac panic; N121 placebo panic). Patients in the 8-week studies received hcl either 20 or 60 mg/day of prozac or placebo in the morning. Instead, the best way to dispose of your medication is through a medicine take-back fluoxetine program. Understanding Depression Slideshow, take the Depression Quiz, depression Tips Slideshow Pictures. Adults: Initially, 20 mg/day.O. However, due to higher plasma levels in lower weight children, the starting and target dose in this group may be 10 mg/day. Difficulty sleeping, new or worse irritability, being aggressive, angry, or violent. No reports involved the administration of methylene blue by hcl other routes (such as oral tablets or local tissue injection) or at lower doses. Tell your doctor if any of these symptoms are severe or do fluoxetine not go away: nervousness anxiety hcl difficulty falling asleep or staying asleep nausea diarrhea dry mouth heartburn yawning weakness uncontrollable shaking of a part of the body. Phospholipid accumulation in animals has been observed with many cationic amphiphilic drugs, including fenfluramine, imipramine, and ranitidine. Avoid the concomitant use of drugs known to prolong the QT interval. Treatment resistant depression (Major Depressive Disorder in patients, who do not respond to 2 separate trials of different antidepressants of adequate dose and duration in the current episode). What should I hcl tell my healthcare provider before taking prozac? You also can obtain the Medication Guide from the FDA website:. Symptoms such as these may be associated with an increased risk fluoxetine for suicidal thinking and behavior and indicate a need for very close monitoring and possibly changes in the medication see BOX warning and warnings AND precautions. It is generally believed (though not established in controlled trials) that treating such an episode with an antidepressant alone may increase the likelihood of precipitation of a mixed/ manic episode in patients at risk for Bipolar Disorder. Limited evidence is available concerning the longer-term effects of fluoxetine on the development and maturation of children and adolescent patients. In a patient who requires more urgent treatment of a psychiatric condition, fluoxetine other interventions, including hospitalization, should be considered see contraindications. Voluntary reports of adverse reactions temporally associated with prozac that have been received since market introduction and that may have no causal relationship with the drug include the following: aplastic anemia, atrial fibrillation 1, cataract, cerebrovascular accident 1, cholestatic jaundice.
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